Cysteinyl leukotrienes mediate the enhancing effects of indomethacin and aspirin on eosinophil production in murine bone marrow cultures

BACKGROUND: Prostaglandin E(2) (PGE(2)) suppresses, while indomethacin and aspirin enhance, eosinophil production in murine liquid bone-marrow cultures. Because cysteinyl leukotrienes (cys-LTs) enhance human eosinophil colony formation, we investigated whether the effects of indomethacin and aspirin...

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Detalhes bibliográficos
Main Authors: Elsas, P X, Queto, T, Mendonça-Sales, S C, Elsas, M I G, Kanaoka, Y, Lam, B K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2241793/
https://ncbi.nlm.nih.gov/pubmed/18037915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707586
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