Protein Tyrosine Phosphatases, TC-PTP, SHP1, and SHP2, Cooperate in Rapid Dephosphorylation of Stat3 in Keratinocytes Following UVB Irradiation

Stat3 is initially dephosphorylated in murine keratinocytes in response to UVB irradiation. Treatment with Na(3)VO(4) desensitized keratinocytes to UVB-induced apoptosis with the recovery of phosphorylated Stat3 protein levels, implying that a protein tyrosine phosphatase (PTP) is involved in this m...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Kim, Dae Joon, Tremblay, Michel L., DiGiovanni, John
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2010
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858656/
https://ncbi.nlm.nih.gov/pubmed/20421975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010290
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