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STAT3 controls the neutrophil migratory response to CXCR2 ligands by direct activation of G-CSF–induced CXCR2 expression and via modulation of CXCR2 signal transduction

Neutrophil mobilization, the release of neutrophils from the bone marrow reserve into circulating blood, is important to increase peripheral neutrophil amounts during bacterial infections. Granulocyte colony-stimulating factor (G-CSF) and chemokines, such as macrophage-inflammatory protein-2 (MIP-2;...

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Bibliografiske detaljer
Main Authors: Nguyen-Jackson, Hoainam, Panopoulos, Athanasia D., Zhang, Huiyuan, Li, Haiyan S., Watowich, Stephanie S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858484/
https://ncbi.nlm.nih.gov/pubmed/20185584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-240317
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