G-CSF–mediated thrombopoietin release triggers neutrophil motility and mobilization from bone marrow via induction of Cxcr2 ligands

Emergency mobilization of neutrophil granulocytes (neutrophils) from the bone marrow (BM) is a key event of early cellular immunity. The hematopoietic cytokine granulocyte-colony stimulating factor (G-CSF) stimulates this process, but it is unknown how individual neutrophils respond in situ. We show...

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Main Authors: Köhler, Anja, De Filippo, Katia, Hasenberg, Mike, van den Brandt, Cindy, Nye, Emma, Hosking, Martin P., Lane, Thomas E., Männ, Linda, Ransohoff, Richard M., Hauser, Anja E., Winter, Oliver, Schraven, Burkhart, Geiger, Hartmut, Hogg, Nancy, Gunzer, Matthias
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2011
主題:
Phagocytes, Granulocytes, and Myelopoiesis
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087483/
https://ncbi.nlm.nih.gov/pubmed/21224471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-09-308387
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