Alternative modes of GM-CSF receptor activation revealed using activated mutants of the common β-subunit

Granulocyte/macrophage colony-stimulating factor promotes growth, survival, differentiation, and activation of normal myeloid cells and plays an important role in myeloid leukemias. The GM-CSF receptor (GMR) shares a signaling subunit, β(c), with interleukin-3 and interleukin-5 receptors and has rec...

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Autores principales: Perugini, Michelle, Brown, Anna L., Salerno, Diana G., Booker, Grant W., Stojkoski, Cvetan, Hercus, Timothy R., Lopez, Angel F., Hibbs, Margaret L., Gonda, Thomas J., D'Andrea, Richard J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2010
Materias:
Phagocytes, Granulocytes, and Myelopoiesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858480/
https://ncbi.nlm.nih.gov/pubmed/20173116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-235846
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