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Transgenic Humanized AHR Mouse Reveals Differences between Human and Mouse AHR Ligand Selectivity

The Aryl-hydrocarbon receptor (AHR) is a ligand activated transcription factor involved in xenobiotic metabolism. Most of the toxic effects of halogenated and non-halogenated polycyclic aromatic hydrocarbons (HAHs and PAHs respectively) are mediated by the AHR. For the AHR, a number of intra and int...

詳細記述

保存先:
書誌詳細
主要な著者: Flaveny, Colin A., Perdew, Gary H.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858462/
https://ncbi.nlm.nih.gov/pubmed/20419055
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