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Transgenic Humanized AHR Mouse Reveals Differences between Human and Mouse AHR Ligand Selectivity

The Aryl-hydrocarbon receptor (AHR) is a ligand activated transcription factor involved in xenobiotic metabolism. Most of the toxic effects of halogenated and non-halogenated polycyclic aromatic hydrocarbons (HAHs and PAHs respectively) are mediated by the AHR. For the AHR, a number of intra and int...

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Detalhes bibliográficos
Main Authors: Flaveny, Colin A., Perdew, Gary H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858462/
https://ncbi.nlm.nih.gov/pubmed/20419055
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