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Dendritic cell podosomes are protrusive and invade the extracellular matrix using metalloproteinase MMP-14

Podosomes are spot-like actin-rich structures formed at the ventral surface of monocytic and haematopoietic cells. Podosomes degrade extracellular matrix and are proposed to be involved in cell migration. A key question is whether podosomes form protrusions similar to the invadopodia of cancer cells...

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Autors principals: Gawden-Bone, Christian, Zhou, Zhongjun, King, Emma, Prescott, Alan, Watts, Colin, Lucocq, John
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858019/
https://ncbi.nlm.nih.gov/pubmed/20356925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.056515
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