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The Human SepSecS-tRNA(Sec) Complex Reveals the Mechanism of Selenocysteine Formation
Selenocysteine is the only genetically encoded amino acid in humans whose biosynthesis occurs on its cognate transfer RNA (tRNA). O-Phosphoseryl-tRNA:selenocysteinyl-tRNA synthase (SepSecS) catalyzes the final step of selenocysteine formation by a poorly understood tRNA-dependent mechanism. The crys...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2857584/ https://ncbi.nlm.nih.gov/pubmed/19608919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1173755 |
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