Evaluation of hemostasis and endothelial function in patients with paroxysmal nocturnal hemoglobinuria receiving eculizumab

BACKGROUND: Paroxysmal nocturnal hemoglobinuria (PNH) is associated with an increased risk of thrombosis through unknown mechanisms. DESIGN AND METHODS: We studied 23 patients with PNH, before and after five and 11 weeks of treatment with eculizumab. We examined markers of thrombin generation and re...

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Hauptverfasser: Helley, Dominique, de Latour, Régis Peffault, Porcher, Raphaël, Rodrigues, Celso Arrais, Galy-Fauroux, Isabelle, Matheron, Jeanne, Duval, Arnaud, Schved, Jean-François, Fischer, Anne-Marie, Socié, Gérard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ferrata Storti Foundation 2010
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857186/
https://ncbi.nlm.nih.gov/pubmed/20081060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.016121
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