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Tied Up in Loops: Positive and Negative Autoregulation of p53
The tumor suppressor p53 is a master sensor of stress that controls many biological functions, including implantation, cell-fate decisions, metabolism, and aging. In response to a defined stress signal such as gamma radiation, the response of p53 is heterogeneous in vivo. Like a complex barcode, the...
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2010
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2857175/ https://ncbi.nlm.nih.gov/pubmed/20452957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a000984 |
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