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Potential positive and negative autoregulation of p60c-src by intermolecular autophosphorylation.

The product of the protooncogene c-src is a protein-tyrosine kinase, p60c-src, that is normally inhibited by phosphorylation at a tyrosine residue close to the C terminus (Tyr-527). If activated by dephosphorylation of Tyr-527, or by other means, p60c-src becomes phosphorylated at a tyrosine residue...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Cooper, J A, MacAuley, A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280401/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2454466/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.12.4232
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