Potential positive and negative autoregulation of p60c-src by intermolecular autophosphorylation.
The product of the protooncogene c-src is a protein-tyrosine kinase, p60c-src, that is normally inhibited by phosphorylation at a tyrosine residue close to the C terminus (Tyr-527). If activated by dephosphorylation of Tyr-527, or by other means, p60c-src becomes phosphorylated at a tyrosine residue...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1988
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280401/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2454466/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.12.4232 |
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