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Tied Up in Loops: Positive and Negative Autoregulation of p53

The tumor suppressor p53 is a master sensor of stress that controls many biological functions, including implantation, cell-fate decisions, metabolism, and aging. In response to a defined stress signal such as gamma radiation, the response of p53 is heterogeneous in vivo. Like a complex barcode, the...

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Detalhes bibliográficos
Autor principal: Lu, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857175/
https://ncbi.nlm.nih.gov/pubmed/20452957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a000984
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