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A Proteome-wide Analysis of Kinase-Substrate Network in the DNA Damage Response

The DNA damage checkpoint, consisting of an evolutionarily conserved protein kinase cascade, controls the DNA damage response in eukaryotes. Knowledge of the in vivo substrates of the checkpoint kinases is essential toward understanding their functions. Here we used quantitative mass spectrometry to...

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Detalhes bibliográficos
Main Authors: Chen, Sheng-hong, Albuquerque, Claudio P., Liang, Jason, Suhandynata, Raymond T., Zhou, Huilin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857137/
https://ncbi.nlm.nih.gov/pubmed/20190278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.106989
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