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A Proteome-wide Analysis of Kinase-Substrate Network in the DNA Damage Response

The DNA damage checkpoint, consisting of an evolutionarily conserved protein kinase cascade, controls the DNA damage response in eukaryotes. Knowledge of the in vivo substrates of the checkpoint kinases is essential toward understanding their functions. Here we used quantitative mass spectrometry to...

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Main Authors: Chen, Sheng-hong, Albuquerque, Claudio P., Liang, Jason, Suhandynata, Raymond T., Zhou, Huilin
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2010
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857137/
https://ncbi.nlm.nih.gov/pubmed/20190278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.106989
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