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A Proteome-wide Analysis of Kinase-Substrate Network in the DNA Damage Response

The DNA damage checkpoint, consisting of an evolutionarily conserved protein kinase cascade, controls the DNA damage response in eukaryotes. Knowledge of the in vivo substrates of the checkpoint kinases is essential toward understanding their functions. Here we used quantitative mass spectrometry to...

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Autores principales: Chen, Sheng-hong, Albuquerque, Claudio P., Liang, Jason, Suhandynata, Raymond T., Zhou, Huilin
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857137/
https://ncbi.nlm.nih.gov/pubmed/20190278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.106989
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