The Anti-tumorigenic Properties of Peroxisomal Proliferator-activated Receptor α Are Arachidonic Acid Epoxygenase-mediated

Prevalence and mortality make cancer a health challenge in need of effective and better tolerated therapeutic approaches, with tumor angiogenesis identified as a promising target for drug development. The epoxygenase products, the epoxyeicosatrienoic acids, are pro-angiogenic, and down-regulation of...

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Главные авторы: Pozzi, Ambra, Popescu, Vlad, Yang, Shilin, Mei, Shaojun, Shi, Mingjian, Puolitaival, Satu M., Caprioli, Richard M., Capdevila, Jorge H.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2010
Предметы:
Molecular Bases of Disease
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857132/
https://ncbi.nlm.nih.gov/pubmed/20178979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.081554
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