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Morphine-like Opiates Selectively Antagonize Receptor-Arrestin Interactions
The addictive potential of opioids may be related to their differential ability to induce G protein signaling and endocytosis. We compared the ability of 20 ligands (sampled from the main chemical classes of opioids) to promote the association of μ and δ receptors with G protein or β-arrestin 2. Rec...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2857100/ https://ncbi.nlm.nih.gov/pubmed/20189994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.059410 |
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