Foxp1/2/4-NuRD Interactions Regulate Gene Expression and Epithelial Injury Response in the Lung via Regulation of Interleukin-6

To determine the underlying mechanism of Foxp1/2/4-mediated transcriptional repression, a yeast two-hybrid screen was performed that identified p66β, a transcriptional repressor and component of the NuRD chromatin-remodeling complex. We show that direct interactions between Foxp1/4 and p66β are medi...

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Main Authors: Chokas, Ann L., Trivedi, Chinmay M., Lu, Min Min, Tucker, Philip W., Li, Shanru, Epstein, Jonathan A., Morrisey, Edward E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Developmental Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857082/
https://ncbi.nlm.nih.gov/pubmed/20185820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.088468
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