Structural Basis of Membrane Targeting by the Dock180 Family of Rho Family Guanine Exchange Factors (Rho-GEFs)

The Dock180 family of atypical Rho family guanine nucleotide exchange factors (Rho-GEFs) regulate a variety of processes involving cellular or subcellular polarization, including cell migration and phagocytosis. Each contains a Dock homology region-1 (DHR-1) domain that is required to localize its G...

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Główni autorzy: Premkumar, Lakshmanane, Bobkov, Andrey A., Patel, Manishha, Jaroszewski, Lukasz, Bankston, Laurie A., Stec, Boguslaw, Vuori, Kristiina, Côté, Jean-Francois, Liddington, Robert C.
Format: Artigo
Język:Inglês
Wydane: American Society for Biochemistry and Molecular Biology 2010
Hasła przedmiotowe:
Protein Structure and Folding
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857062/
https://ncbi.nlm.nih.gov/pubmed/20167601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.102517
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