Human Biliverdin Reductase Suppresses Goodpasture Antigen-binding Protein (GPBP) Kinase Activity: THE REDUCTASE REGULATES TUMOR NECROSIS FACTOR-α-NF-κB-DEPENDENT GPBP EXPRESSION

The Ser/Thr/Tyr kinase activity of human biliverdin reductase (hBVR) and the expression of Goodpasture antigen-binding protein (GPBP), a nonconventional Ser/Thr kinase for the type IV collagen of basement membrane, are regulated by tumor necrosis factor (TNF-α). The pro-inflammatory cytokine stimula...

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Detalhes bibliográficos
Main Authors: Miralem, Tihomir, Gibbs, Peter E. M., Revert, Fernando, Saus, Juan, Maines, Mahin D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857060/
https://ncbi.nlm.nih.gov/pubmed/20177069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.032771
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