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Immunosuppressive Cyclosporin A Activates AKT in Keratinocytes through PTEN Suppression: IMPLICATIONS IN SKIN CARCINOGENESIS
Non-melanoma skin cancer, the most common neoplasia after solid organ transplantation, causes serious morbidity and mortality and is related to sun exposure. Cyclosporin A (CsA) has been used widely to prevent rejection in organ transplantation. The mechanism of CsA action in causing cancer was thou...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2857015/ https://ncbi.nlm.nih.gov/pubmed/20154081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.028142 |
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