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Studies of the Maltose Transport System Reveal a Mechanism for Coupling ATP Hydrolysis to Substrate Translocation without Direct Recognition of Substrate

The ATPase activity of the maltose transporter (MalFGK(2)) is dependent on interactions with the maltose-binding protein (MBP). To determine whether direct interactions between the translocated sugar and MalFGK(2) are important for the regulation of ATP hydrolysis, we used an MBP mutant (sMBP) that...

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Bibliographic Details
Main Authors: Gould, Alister D., Shilton, Brian H.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857007/
https://ncbi.nlm.nih.gov/pubmed/20147285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.089078
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