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Sequential Action of MalE and Maltose Allows Coupling ATP Hydrolysis to Translocation in the MalFGK(2) Transporter

ATP-binding cassette (ABC) transporters have evolved an ATP-dependent alternating-access mechanism to transport substrates across membranes. Despite important progress, especially in their structural analysis, it is still unknown how the substrate stimulates ATP hydrolysis, the hallmark of ABC trans...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Bao, Huan, Dalal, Kush, Cytrynbaum, Eric, Duong, Franck
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646192/
https://ncbi.nlm.nih.gov/pubmed/26338707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.671826
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