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Beyond the Canonical 20 Amino Acids: Expanding the Genetic Lexicon
The ability to genetically encode unnatural amino acids beyond the common 20 has allowed unprecedented control over the chemical structures of recombinantly expressed proteins. Orthogonal aminoacyl-tRNA synthetase/tRNA pairs have been used together with nonsense, rare, or 4-bp codons to incorporate...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856976/ https://ncbi.nlm.nih.gov/pubmed/20147747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R109.091306 |
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