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Recombinant Macrocyclic Lanthipeptides Incorporating Non-Canonical Amino Acids
Nisin is a complex lanthipeptide that has broad spectrum antibacterial activity. In efforts to broaden the structural diversity of this ribosomally synthesized lantibiotic, we now report the recombinant expression of Nisin variants that incorporate non-canonical amino acids (ncAAs) at discrete posit...
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| Veröffentlicht in: | J Am Chem Soc |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5847277/ https://ncbi.nlm.nih.gov/pubmed/28809560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b04159 |
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