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Caspase-cleaved TAR DNA-binding protein-43 in Pick's disease

The hyperphosphorylation and proteolytic modification of the TAR DNA binding protein-43 (TDP-43) is a key finding in a number of neurodegenerative diseases including frontotemporal dementia with ubiquitin-positive inclusions (FTLD-U), amyotrophic lateral sclerosis (ALS), and most recently Alzheimer&...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rohn, Troy T, Kokoulina, Polina
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856940/
https://ncbi.nlm.nih.gov/pubmed/20411029
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