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αvβ3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and migration

Integrins are fundamental to the control of protrusion and motility in adherent cells. However, the mechanisms by which specific members of this receptor family cooperate in signaling to cytoskeletal and adhesion dynamics are poorly understood. Here, we show that the loss of β3 integrin in fibroblas...

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Detalhes bibliográficos
Main Authors: Worth, Daniel C., Hodivala-Dilke, Kairbaan, Robinson, Stephen D., King, Samantha J., Morton, Penny E., Gertler, Frank B., Humphries, Martin J., Parsons, Maddy
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856911/
https://ncbi.nlm.nih.gov/pubmed/20404115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200912014
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