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c-Myb promotes the survival of CD4+CD8+ double positive thymocytes through up-regulation of Bcl-xL
Mechanisms that regulate the lifespan of CD4(+)CD8(+) double positive (DP) thymocytes help shape the peripheral T cell repertoire. However, the molecular mechanisms that control DP thymocyte survival remain poorly understood. The Myb proto-oncogene encodes a transcription factor required during mult...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856624/ https://ncbi.nlm.nih.gov/pubmed/20142358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902846 |
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