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Functional Residues on the Surface of the N-terminal domain of Yeast Pms1
Saccharomyces cerevisiae MutLα is a heterodimer of Mlh1 and Pms1 that participates in DNA mismatch repair (MMR). Both proteins have weakly conserved C-terminal regions (CTD), with the CTD of Pms1 harboring an essential endonuclease activity. These proteins also have conserved N-terminal domains (NTD...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856611/ https://ncbi.nlm.nih.gov/pubmed/20138591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.01.010 |
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