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Early Intermediate in Human Prion Protein Folding as Evidenced by Ultrarapid Mixing Experiments
An important step towards understanding the mechanism of the PrP(C) to PrP(Sc) conversion is to elucidate the folding pathway(s) of the prion protein. Based on stopped-flow measurements, we recently proposed that the prion protein folds via a transient intermediate formed on the sub-millisecond time...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856597/ https://ncbi.nlm.nih.gov/pubmed/16939293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja063880b |
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