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An Adaptor Domain-Mediated Auto-Catalytic Interfacial Kinase Reaction

This paper describes a model system for studying the auto-catalytic phosphorylation of an immobilized substrate by a kinase enzyme. This work uses self-assembled monolayers (SAMs) of alkanethiolates on gold to present the peptide substrate on a planar surface. Treatment of the monolayer with Abl kin...

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Main Authors: Liao, Xiaoli, Su, Jing, Mrksich, Milan
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856317/
https://ncbi.nlm.nih.gov/pubmed/19821459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.200901345
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