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Composition of receptor tyrosine kinase-mediated lipid micro-domains controlled by adaptor protein interaction

Receptor tyrosine kinases (RTKs) are highly regulated, single pass transmembrane proteins, fundamental to cellular function and survival. Aberrancies in regulation lead to corruption of signal transduction and a range of pathological outcomes. Although control mechanisms associated with the receptor...

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Publicat a:Sci Rep
Autors principals: Rohwedder, Arndt, Knipp, Sabine, Roberts, Lee D., Ladbury, John E.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969938/
https://ncbi.nlm.nih.gov/pubmed/33731760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-85578-8
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