A Critical Role for Ceramide Synthase 2 in Liver Homeostasis: I. ALTERATIONS IN LIPID METABOLIC PATHWAYS

Ceramide is an important lipid signaling molecule that plays critical roles in regulating cell behavior. Ceramide synthesis is surprisingly complex and is orchestrated by six mammalian ceramide synthases, each of which produces ceramides with restricted acyl chain lengths. We have generated a CerS2...

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Autori principali: Pewzner-Jung, Yael, Park, Hyejung, Laviad, Elad L., Silva, Liana C., Lahiri, Sujoy, Stiban, Johnny, Erez-Roman, Racheli, Brügger, Britta, Sachsenheimer, Timo, Wieland, Felix, Prieto, Manuel, Merrill, Alfred H., Futerman, Anthony H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
Soggetti:
Lipids
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856296/
https://ncbi.nlm.nih.gov/pubmed/20110363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.077594
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