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Sphingosine 1-Phosphate Lyase Deficiency Disrupts Lipid Homeostasis in Liver
The cleavage of sphingoid base phosphates by sphingosine-1-phosphate (S1P) lyase to produce phosphoethanolamine and a fatty aldehyde is the final degradative step in the sphingolipid metabolic pathway. We have studied mice with an inactive S1P lyase gene and have found that, in addition to the expec...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856294/ https://ncbi.nlm.nih.gov/pubmed/20097939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.081489 |
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