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Human ELG1 Regulates the Level of Ubiquitinated Proliferating Cell Nuclear Antigen (PCNA) through Its Interactions with PCNA and USP1

The level of monoubiquitinated proliferating cell nuclear antigen (PCNA) is closely linked with DNA damage bypass to protect cells from a high level of mutagenesis. However, it remains unclear how the level of monoubiquitinated PCNA is regulated. Here, we demonstrate that human ELG1 protein, which c...

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Autors principals: Lee, Kyoo-young, Yang, Kailin, Cohn, Martin A., Sikdar, Nilabja, D'Andrea, Alan D., Myung, Kyungjae
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856242/
https://ncbi.nlm.nih.gov/pubmed/20147293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.092544
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