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Human ELG1 Regulates the Level of Ubiquitinated Proliferating Cell Nuclear Antigen (PCNA) through Its Interactions with PCNA and USP1

The level of monoubiquitinated proliferating cell nuclear antigen (PCNA) is closely linked with DNA damage bypass to protect cells from a high level of mutagenesis. However, it remains unclear how the level of monoubiquitinated PCNA is regulated. Here, we demonstrate that human ELG1 protein, which c...

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מידע ביבליוגרפי
Main Authors: Lee, Kyoo-young, Yang, Kailin, Cohn, Martin A., Sikdar, Nilabja, D'Andrea, Alan D., Myung, Kyungjae
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856242/
https://ncbi.nlm.nih.gov/pubmed/20147293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.092544
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