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Developmental Silencing of Human ζ-Globin Gene Expression Is Mediated by the Transcriptional Repressor RREB1

The mammalian embryonic ζ-globin genes, including that of humans, are expressed at the early embryonic stage and then switched off during erythroid development. This autonomous silencing of the ζ-globin gene transcription is probably regulated by the cooperative work of various protein-DNA and prote...

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Библиографические подробности
Главные авторы: Chen, Ruei-Lin, Chou, Yu-Chi, Lan, Yii-Jenq, Huang, Ting-Shuo, Shen, C.-K. James
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856224/
https://ncbi.nlm.nih.gov/pubmed/20133935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.049130
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