Anti-phospholipid human monoclonal antibodies inhibit CCR5-tropic HIV-1 and induce β-chemokines

Traditional antibody-mediated neutralization of HIV-1 infection is thought to result from the binding of antibodies to virions, thus preventing virus entry. However, antibodies that broadly neutralize HIV-1 are rare and are not induced by current vaccines. We report that four human anti-phospholipid...

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Main Authors: Moody, M. Anthony, Liao, Hua-Xin, Alam, S. Munir, Scearce, Richard M., Plonk, M. Kelly, Kozink, Daniel M., Drinker, Mark S., Zhang, Ruijun, Xia, Shi-Mao, Sutherland, Laura L., Tomaras, Georgia D., Giles, Ian P., Kappes, John C., Ochsenbauer-Jambor, Christina, Edmonds, Tara G., Soares, Melina, Barbero, Gustavo, Forthal, Donald N., Landucci, Gary, Chang, Connie, King, Steven W., Kavlie, Anita, Denny, Thomas N., Hwang, Kwan-Ki, Chen, Pojen P., Thorpe, Philip E., Montefiori, David C., Haynes, Barton F.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856026/
https://ncbi.nlm.nih.gov/pubmed/20368576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091281
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