An HIV-1 gp120 Envelope Human Monoclonal Antibody That Recognizes a C1 Conformational Epitope Mediates Potent Antibody-Dependent Cellular Cytotoxicity (ADCC) Activity and Defines a Common ADCC Epitope in Human HIV-1 Serum

Among nonneutralizing HIV-1 envelope antibodies (Abs), those capable of mediating antibody-dependent cellular cytotoxicity (ADCC) activity have been postulated to be important for control of HIV-1 infection. ADCC-mediating Ab must recognize HIV-1 antigens expressed on the membrane of infected cells...

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Hlavní autoři: Ferrari, Guido, Pollara, Justin, Kozink, Daniel, Harms, Tiara, Drinker, Mark, Freel, Stephanie, Moody, M. Anthony, Alam, S. Munir, Tomaras, Georgia D., Ochsenbauer, Christina, Kappes, John C., Shaw, George M., Hoxie, James A., Robinson, James E., Haynes, Barton F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126567/
https://ncbi.nlm.nih.gov/pubmed/21543485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00171-11
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