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Ectodomain shedding of Fcα receptor is mediated by ADAM10 and ADAM17

FcαR (CD89) plays important roles in immunoglobulin A (IgA)-mediated immune responses. Soluble forms of FcαR (sFcαR) are found in the culture supernatants of FcαR-expressing cells, in human serum and in the serum of FcαR transgenic mice, and have been suggested to be produced through a proteolytic p...

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Détails bibliographiques
Auteurs principaux: Peng, Min, Guo, Sha, Yin, Na, Xue, Jing, Shen, Lian, Zhao, Qing, Zhang, Wei
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855796/
https://ncbi.nlm.nih.gov/pubmed/20059578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2009.03215.x
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