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αB-crystallin is mutant B-RAF regulated and contributes to cyclin D1 turnover in melanocytic cells
SUMMARY: The serine/threonine kinase, B-RAF, is frequently mutated in melanoma and is required for cell proliferation. Proteasomal turnover of cyclins and cyclin-dependent kinase inhibitors via E3 ubiquitin ligases regulates cell cycle progression. We previously showed that B-RAF regulates Cks1, a c...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2855751/ https://ncbi.nlm.nih.gov/pubmed/20067552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2010.00668.x |
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