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αB-crystallin is mutant B-RAF regulated and contributes to cyclin D1 turnover in melanocytic cells

SUMMARY: The serine/threonine kinase, B-RAF, is frequently mutated in melanoma and is required for cell proliferation. Proteasomal turnover of cyclins and cyclin-dependent kinase inhibitors via E3 ubiquitin ligases regulates cell cycle progression. We previously showed that B-RAF regulates Cks1, a c...

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Detaylı Bibliyografya
Asıl Yazarlar: Hu, Rong, Aplin, Andrew E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855751/
https://ncbi.nlm.nih.gov/pubmed/20067552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2010.00668.x
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