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Heparanase Promotes Engraftment and Prevents Graft versus Host Disease in Stem Cell Transplantation
BACKGROUND: Heparanase, endoglycosidase that cleaves heparan sulfate side chains of heparan sulfate proteoglycans, plays important roles in cancer metastasis, angiogenesis and inflammation. DESIGN AND METHODS: Applying a mouse model of bone marrow transplantation and transgenic mice over-expressing...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2855345/ https://ncbi.nlm.nih.gov/pubmed/20419162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010135 |
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