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Alcohol-Induced IGF-I Resistance Is Ameliorated in Mice Deficient for Mitochondrial Branched-Chain Aminotransferase

Acute alcohol intoxication decreases skeletal muscle protein synthesis by impairing mammalian target of rapamycin (mTOR). In 2 studies, we determined whether inhibition of branched-chain amino acid (BCAA) catabolism ameliorates the inhibitory effect of alcohol on muscle protein synthesis by raising...

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Bibliografische gegevens
Hoofdauteurs: Lang, Charles H., Lynch, Christopher J., Vary, Thomas C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Nutrition 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855262/
https://ncbi.nlm.nih.gov/pubmed/20237068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.109.120501
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