Mice deficient in the mitochondrial branched-chain aminotransferase (BCATm) respond with delayed tumour growth to a challenge with EL-4 lymphoma

BACKGROUND: The mitochondrial branched-chain aminotransferase (BCATm) is a recently discovered cancer marker with a poorly defined role in tumour progression. METHODS: To understand how a loss of function of BCATm affects cancer, the global knockout mouse BCATmKO was challenged with EL-4 lymphoma un...

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Bibliografske podrobnosti
izdano v:Br J Cancer
Main Authors: Ananieva, Elitsa A., Bostic, Joshua N., Torres, Ashley A., Glanz, Hannah R., McNitt, Sean M., Brenner, Michelle K., Boyer, Michael P., Addington, Adele K., Hutson, Susan M.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203766/
https://ncbi.nlm.nih.gov/pubmed/30318512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0283-7
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