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Robust Hepatic Gene Silencing for Functional Studies Using Helper-Dependent Adenoviral Vectors

RNA interference is currently envisioned as the basis of gene function and drug target validation studies. This novel technology has the advantage of providing a remarkably faster tool for gene silencing than traditional transgenic animal methodologies. In vivo administration of short interfering RN...

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Detalhes bibliográficos
Main Authors: Ruiz, Rafaela, Witting, Scott R., Saxena, Romil, Morral, Núria
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855247/
https://ncbi.nlm.nih.gov/pubmed/18828727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2008.081
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