Učitavanje...
Inter-subunit capture of regulatory segments is a component of cooperative CaMKII activation
The dodecameric holoenzyme of Calcium-calmodulin dependent protein kinase II (CaMKII) responds to high frequency Ca(2+) pulses to become Ca(2+) independent. A simple coincidence detector model for Ca(2+)-frequency dependency assumes non-cooperative activation of kinase domains. We show that activati...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2855215/ https://ncbi.nlm.nih.gov/pubmed/20139983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1751 |
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