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Activation-triggered subunit exchange between CaMKII holoenzymes facilitates the spread of kinase activity
The activation of the dodecameric Ca(2+)/calmodulin dependent kinase II (CaMKII) holoenzyme is critical for memory formation. We now report that CaMKII has a remarkable property, which is that activation of the holoenzyme triggers the exchange of subunits between holoenzymes, including unactivated o...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
eLife Sciences Publications, Ltd
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3901001/ https://ncbi.nlm.nih.gov/pubmed/24473075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01610 |
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