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AAV2-mediated gene transfer of GDNF to the striatum of MPTP monkeys enhances the survival and outgrowth of co-implanted fetal dopamine neurons

Neural transplantation offers the potential of treating Parkinson’s disease by grafting fetal dopamine neurons to depleted regions of the brain. However, clinical studies of neural grafting in Parkinson’s disease have produced only modest improvements. One of the main reasons for this is the low sur...

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Detalhes bibliográficos
Main Authors: Elsworth, JD, Redmond, DE, Leranth, C, Bjugstad, KB, Sladek, JR, Collier, TJ, Foti, SB, Samulski, RJ, Vives, KP, Roth, RH
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855210/
https://ncbi.nlm.nih.gov/pubmed/18346734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2008.01.026
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